HSP90B1 ELISA Kit for Human(Homo sapiens) | EIAab.comHSP90B1 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > HSP90B1(Gene name) > Human

HSP90B1 (Gene name),

Endoplasmin (Protein name ), ENPL_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

HSP90B1(GRP94;TRA1);

Protein name:

Endoplasmin;

Alternative:

Heat shock protein 90 kDa beta member 1;94 kDa glucose-regulated protein(GRP-94);gp96 homolog;Tumor rejection antigen 1;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Homodimer; disulfide-linked. Component of an EIF2 complex at least composed of CELF1/CUGBP1, CALR, CALR3, EIF2S1, EIF2S2, HSP90B1 and HSPA5 (By similarity). Part a large chaperone multiprotein complex comprising DNAJB11, HSP90B1, HSPA5, HYOU, PDIA2, PDIA4, PDIA6, PPIB, SDF2L1, UGT1A1 and very small amounts of ERP29, but not, or at very low levels, CALR nor CANX. Interacts with AIMP1; regulates its retention in the endoplasmic reticulum. Interacts with OS9.

Function:

Molecular chaperone that functions in the processing and transport of secreted proteins. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity.

Subcellular Location:

Endoplasmic reticulum lumen Melanosome Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Protein Attributes:

Sequence length:

803

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

803:

DEL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF02518

STRING:

9606.ENSP00000299767

KEGG:

hsa:7184

String:

P14625

SMR:

P14625

Pfam:

PF00183

UniGene:

Hs.192374

MIM:

191175

Uniprot:

P14625

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ELISA Kit for Human Endoplasmin

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E0823h

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96T

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ELISA Kit for Human Endoplasmin

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E0823m

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96T

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ELISA Kit for Human Endoplasmin

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ELISA Kit for Human Endoplasmin

Cat.:

E0823d

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96T

ELISA Kit for Human Endoplasmin

Cat.:

E0823c

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96T

ELISA Kit for Human Endoplasmin

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E0823p

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96T

ELISA Kit for Human Endoplasmin

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E0823b

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96T

ELISA Kit for Human Endoplasmin

Cat.:

E0823r

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96T

CLIA Kit for Human Endoplasmin

Cat.:

U0823d

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96T

CLIA Kit for Human Endoplasmin

Cat.:

U0823c

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96T

CLIA Kit for Human Endoplasmin

Cat.:

U0823h

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96T

CLIA Kit for Human Endoplasmin

MSDS:

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CLIA Kit for Human Endoplasmin

Cat.:

U0823m

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96T

CLIA Kit for Human Endoplasmin

Cat.:

U0823r

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96T

CLIA Kit for Human Endoplasmin

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U0823b

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96T

CLIA Kit for Human Endoplasmin

Cat.:

U0823p

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96T

Polyclonal Antibody for Human Endoplasmin

Cat.:

P0823Rb-r

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40ug/0.2ml

Polyclonal Antibody for Human Endoplasmin

Cat.:

P0823Rb-m

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Polyclonal Antibody for Human Endoplasmin

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P0823Rb-h

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Polyclonal Antibody for Human Endoplasmin

Monoclonal Antibody for Human Endoplasmin

Protein for Human Endoplasmin

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"Human homologue of murine tumor rejection antigen gp96: 5'-regulatory and coding regions and relationship to stress-induced proteins."
Maki R.G. , Old L.J. , Srivastava P.K.
Proc. Natl. Acad. Sci. U.S.A.87:5658-5662(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-16
tissue: Blood.
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Skin.
3.

"Glucose-regulated protein (GRP94 and GRP78) genes share common regulatory domains and are coordinately regulated by common trans-acting factors."
Chang S.C. , Erwin A.E. , Lee A.S.
Mol. Cell. Biol.9:2153-2162(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-16
tissue: Liver.
4.

"The association of heat shock protein gp96 with HBV-derived peptides in vitro."
Meng S. , Tien P.
Submitted (2001-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 22-803
tissue: Liver.
5.

"Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides."
Gevaert K. , Goethals M. , Martens L. , Van Damme J. , Staes A. , Thomas G.R. , Vandekerckhove J.
Nat. Biotechnol.21:566-569(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 22-39
tissue: Platelet.
6.

"A subset of chaperones and folding enzymes form multiprotein complexes in endoplasmic reticulum to bind nascent proteins."
Meunier L. , Usherwood Y.-K. , Chung K.T. , Hendershot L.M.
Mol. Biol. Cell13:4456-4469(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: COMPONENT OF A CHAPERONE COMPLEX
7.

"Proteomic analysis of early melanosomes: identification of novel melanosomal proteins."
Basrur V. , Yang F. , Kushimoto T. , Higashimoto Y. , Yasumoto K. , Valencia J. , Muller J. , Vieira W.D. , Watabe H. , Shabanowitz J. , Hearing V.J. , Hunt D.F. , Appella E.
J. Proteome Res.2:69-79(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS]
tissue: Melanoma.
8.

"Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry."
Zhang H. , Li X.-J. , Martin D.B. , Aebersold R.
Nat. Biotechnol.21:660-666(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT ASN-217 AND ASN-445
9.

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
10.

"Folding of Toll-like receptors by the HSP90 paralogue gp96 requires a substrate-specific cochaperone."
Liu B. , Yang Y. , Qiu Z. , Staron M. , Hong F. , Li Y. , Wu S. , Li Y. , Hao B. , Bona R. , Han D. , Li Z.
Nat. Commun.1:79-79(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CNPY3; TLR4 AND TLR9
11.

Liu B. , Yang Y. , Qiu Z. , Staron M. , Hong F. , Li Y. , Wu S. , Li Y. , Hao B. , Bona R. , Han D. , Li Z.
Nat. Commun.3:653-653(2012)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
12.

"Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes."
Chi A. , Valencia J.C. , Hu Z.-Z. , Watabe H. , Yamaguchi H. , Mangini N.J. , Huang H. , Canfield V.A. , Cheng K.C. , Yang F. , Abe R. , Yamagishi S. , Shabanowitz J. , Hearing V.J. , Wu C. , Appella E. , Hunt D.F.
J. Proteome Res.5:3135-3144(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS]
tissue: Melanoma.
13.

"Elucidation of N-glycosylation sites on human platelet proteins: a glycoproteomic approach."
Lewandrowski U. , Moebius J. , Walter U. , Sickmann A.
Mol. Cell. Proteomics5:226-233(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-107
tissue: Platelet.
14.

"OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD."
Christianson J.C. , Shaler T.A. , Tyler R.E. , Kopito R.R.
Nat. Cell Biol.10:272-282(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH OS9
15.

"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-62; ASN-107; ASN-217 AND ASN-445
tissue: Liver.
16.

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-306;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
17.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
18.

"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-306;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
19.

"A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity."
Cloutier P. , Lavallee-Adam M. , Faubert D. , Blanchette M. , Coulombe B.
PLoS Genet.9:E1003210-E1003210(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH METTL23

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